Tuesday, December 25, 2012

What wealthy Chinese want for Christmas: a bike

15 hrs.

HONG KONG - Rich Chinese are buying bicycles that cost more than the average citizen makes in three years, motivated by nostalgia for the days when two wheels were the primary means of transport.?

China is now the world's biggest auto market, but high-end bike sales are expected to grow by 10 percent a year as they become a status symbol for wealthy executives.?

Yu Yiqun, the creative director at an advertising company in the Chinese capital, cycles to work on his favorite bike - a 100,000 yuan ($16,000) hand-made Alex Moulton.?

"It might be the only one in Beijing. It's like the Rolls-Royce of bicycles. Very classical, purely hand-made," said the 40-year-old Yu, who has about 35 high-end bikes.?

"I remember my father used to ride me to the city in the winter - about 40 km and minus 30 degrees centigrade. Back then, it was a means of transport that fulfilled your dream of travelling afar, which was relatively cheap but required brawn."?

Yu symbolizes a new bike culture in China, where wealthy, health-conscious executives are upgrading their lifestyle, in some cases abandoning flashy cars and taking to the road on high-end bicycles that can cost more than a car.?

"Demand for mainstream luxury items such as premium cars, watches has come to a point of saturation. High-income groups now turn to high-end bikes to show off the uniqueness in taste and healthy lifestyle," said Zhou Jiannong, general manager of Rbike Networks Ltd in China.?

Analysts estimate about 10 percent annual growth in the Chinese bicycle market over the next few years, with the high-end segment forecast to grow by as much as 15 percent a year.?

Companies are also getting in on the act, with a Hong Kong-based supplier taking an order for 1,000 pricey bikes from a Chinese financial firm as a year-end bonus for employees.?

"People are sick of conventional gifts such as wines and tobacco. For mainlanders, a bike is a great gift that shows your unique lifestyle," said Adam Wong, managing director at Hong Kong's Komda Bicycles.?

Wong declined to name the bank that had ordered the bikes, but he said they had an average price tag of 3,000 yuan ($480).?

Fashion statement
Fashion label Shanghai Tang, eager for a slice of this growing pie, teamed up with Dutch bike maker Colossi Cycling to make bicycles aimed specifically at China, where bike demand is estimated at about 28 million units a year?

"The high-end sector is going to be the major source of growth in the Chinese market. In China, bikes are more than just a means of transportation. It has become a fashion," said Terry Liu, an analyst at Fubon Research in Taiwan.?

It can cost up to HK$300,000 ($38,700) for an imported limited edition of expensive brands such as Italy's Colnago or France's Look, nearly 100 times the price of a Flying Pigeon, China's official bike since it was born in 1950.?

But the cost as no object for many high-income Chinese looking for the best two-wheeled vehicle.?

"For businessmen, they are not looking at the price. They are looking at the quality. They assemble their bike with import components in accordance to their taste and needs," said Zhang Lei, a director of a Zhuhai paper products supplier, who plans to spend 10,000 yuan to upgrade his current bike.?

Yu, the advertising executive in Beijing, has orders in for four more hand-made bikes, expanding his vast collection which includes brands such as Trek, Bianchi and Colnago.?

He and his wife have two cars but he says he doesn't drive.?

"I always bring my bike when I go on a business trip," Yu said. "When I go to Harbin, I bring a small, folding bicycle since it's easier for me to get around the city. When I go to Dalian, I bring a bigger bike since it's a mountainous city."?

Source: http://www.nbcnews.com/business/what-wealthy-chinese-want-christmas-bike-1C7660218

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Wednesday, December 19, 2012

96% Sister

All Critics (50) | Top Critics (15) | Fresh (48) | Rotten (2)

"Sister" avoids sentimental indulgence. There's no room for wallowing in this spare, almost ascetic exercise ...

French-born director and co-screenwriter Ursula Meier balances the scenario's bleak, wrenching aspects with a stirring confidence in the redemptive power of love.

Seydoux perfectly captures the anger and self-defeat of ill-educated, hedonistic, man-chasing young women who live on the fringes.

L?a Seydoux fulfills Louise, and Kacey Mottet Klein, as Simon, is one more to join the pantheon of film's excellent child actors.

Haunting and sad. And absolutely worth seeing.

The chemistry between the two leads is a razor's-edge dance: feral, childish, tender and always complex.

The storytelling is exciting and the characters well-observed.

For the most part a distant film, Sister supplies a full behavioral experience that's riveting at times, with lead performances by Lea Seydoux and Kacey Mottet Klein communicating isolation in bravely vulnerable ways.

Emotionally engaging and impeccably crafted

Klein and Seydoux give such naturalistic performances that they're never overwhelmed by the spectacle.

"Sister" is loose and episodic, but held together with nicely sketched characters.

[A]voids bathos. . .reveals unexpected depth in a heartbreaking bond. . . Different classes conflict [in] adjacent spaces . . .in spare, realistic Dardennes' style.

Meier draws out wonderfully naturalistic performances from her young stars, with Mottet Klein particularly good as the young roustabout Simon ...

It comes over like a subtle short story and is well acted.

Meier's portrait of Simon ... is richly atmospheric and never sentimental.

An enigmatic, heartfelt account of a vulnerable young boy's yearning for a better life.

Most intriguing is how the writers and director have transformed what's essentially a rather dark, bleak story into something involving and emotionally resonant, all without ever turning sentimental.

It is an interesting and well-made movie, though with an uncertain ending.

Sister gradually reveals pattern in its tapestry of everyday life.

An expert piece of storytelling with a host of strong character turns and thematic depth to burn.

A healthy seam of mischief helps cut through the occasionally rote social comment.

No quotes approved yet for Sister. Logged in users can submit quotes.

Source: http://www.rottentomatoes.com/m/lenfant_den_haut/

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Wednesday, October 31, 2012

Eating Healthy But Spending Wisely | Frugivore Magazine

Eating healthy doesn?t mean you should have to break your budget or sacrifice taste to do so. It?s easy to get sucked in by grocery merchandising tricks, and it?s also normal for most of us to fall into a mealtime rut, eating the same foods over and over. You can save money and still have quality. A lot of people say that it?s cheaper to eat unhealthy, but with organization and creativity, you can eat healthy on a budget. To start, here?s a quick review of basic tips for healthy eating:

  • Limit your intake of junk food and alcohol
  • Drink lots of water (at least 8 cups a day)
  • Limit salty and sugary foods
  • Avoid eating many foods that are high in saturated fats
  • Make ?variety? the watchword of your eating

Following are a few more hints that can help you save money:

  • When cooking a big meal, make extra to freeze or use later in the week for lunches or quick suppers. Double recipes, then freeze half.
  • Save your vegetable trimmings to make your own vegetable stock. Not only do you save money, but vegetable stock also makes a nutritious base for casseroles, soups, and slow cooker recipes.
  • Buying in bulk is almost always less expensive; you can freeze perishable items (such as meat, milk, and even bread) in smaller portions to use as needed. It?s always a good idea to buy nonperishable items in bulk (canned foods, dried beans and grains, etc.).
  • Use less expensive cuts of meat for casseroles you slow cook; add extra vegetables and beans to make the meal go further. Capitalize on one-pot dishes, which generally save prep time, money, and dishwashing?and often make great leftovers.
  • Limit your dining out, especially when it comes to fast food, since you?ll find yourself spending unnecessarily on items that are high in fat, salt, and calories, which short-change you in the nutrition department.

Source: http://frugivoremag.com/2012/10/eating-healthy-but-spending-wisely/

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Sunday, October 21, 2012

Joint property dispute - legal suggestion request - Indian Real Estate ...

Old 22 Hours Ago ? #1

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Join Date: Oct 2012

Posts: 1


Joint property disputes (among 3 brothers)

i have purchased a plot and constructed house with 02 other brothers. Initially only 02 floors constructed and since then i have been started living in ground floor considering my contribution is much more than their contribution in construction of house. Thereafter on my transfer to other location my two brothers requested me to allow him to live in the house and on posting back to delhi they will vacate the ground floor. On my refusal they started quarreling with me and my family. After living in 5 yrs in the ground floor my both brother made attempt to kill me. On the request of my relatives i agreed to vacate the ground floor and construct second floor. A mou signed and as per conditions i have given six months time for construction of second floor in the house after receiving of fixed amt fm both the brothers. They have made part payment and waited to proceed to my place of duty. On reaching my duty place i have recd a legal notice fm both the brothers stating that i have no right on the said property and threaten to vacate the ground floor otherwise they forceful enter in my ground floor. After 03 months i visited my house i have stunned to see that one of my brother captured my ground floor with all my personal belonging which i kept in the house by forceful opening the doors. After intervention of local police and relatives they have again insisted to sign another agreement and this time they paid the balance amt. On starting construction, they have made all the efforts so that i could not able to construct the second floor and go out of the house. One of my brother who serving in mha at that time started sending representation that i have grabbed the house with ill intention and make all efforts but on my visit to mha they have thrown him out to another ministry. Since they have not agreed to obey the settlement and tried to capture the house by adopting any means i have not started repaying home loan installment fm the date of their illegal capture of my ground floor and now the bank referred the matter to drt for debt recovery.
The summarise case is as under :-
i) sale deed of said plot is among all the three brothers.
Ii) housing loan taken fm bank in the joint name of one of my brother with me and another brother is co-borrower.
Iii) map for construction of 03 floor passed fm gda.
Iv) the house constructed against the approved map.
V) both the agreement are not registered fm court/registaar office despite express order of concerned ssp.
Vi) my both brothers illegally denying my share in the house and sending many representations to my department by themselves and their wives.
Vii) previously one of my brother purchased a flat at gurgaon with my late father's gratuity and i have also contributed as loan and another property purchased at new palam vihar with my second brother's name by using contribution of my late father's payable dues and also fm me. My both brothers are not ready to give back my share in the property and one of the reason for harrashing me for upsurp/grab all joint properties. At the time of purchase of two properties we were living in un-divided hindu family.

Emi deposited by me fm the date of taking the loan mentioned as un-accounted amount in the legal notice served from my brothers.

My case is common to personnel who are serving in Armed Forces who are posted far away from their native place and relatives of such personnel are eyeing on the salary & various allowances they are getting. Due to their very meager expenditure at duty place being providing free boarding & lodging by department and they are very disciplined and always try to out of any illegal activity having close look of conduct by their department.

Kindly intimate legal status of the case.


Last edited by aparanand; 22 Hours Ago at 08:06 PM. Reason: important fact which missed

? Reply With Quote

Source: http://www.indianrealestateforum.com/indian-property-laws-disputes-frauds/t-joint-property-dispute-legal-suggestion-request-44085.html

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Monday, October 15, 2012

Writer Wanna Be's - Copywriting Help

Before my discovery of the internet, in attempting to deal with Christian publishers, I came to realize what preachers have known for a long time. Many publishers use the ?Christian? name for a fast buck. Like others, they want to know who you know and everything else possible that might prove your book will sell [...]

The article starts below...

Written on October 14th, 2012
Read more articles on Become a writer.

Before my discovery of the internet, in attempting to deal with Christian publishers, I came to realize what preachers have known for a long time. Many publishers use the ?Christian? name for a fast buck. Like others, they want to know who you know and everything else possible that might prove your book will sell on the merit of your name, only; without regard to what is actually inside the cover.

They, also, expect you to work so hard at your presentation that the book is ready for publication before submitting. Though, most of the time, it goes into a pile of manuscripts; to barely be skimmed, unless you have already developed a name.

In addition, publishers either want your writing to fit within their specific doctrinal guidelines or they want the writing to be so non-controversial that all religions will accept it. All this is without consideration as to if the Spirit is actually speaking through the writing.

Poetry critiquers don?t like me very well, either. Oh, wait! Maybe it?s the other way around.

First, you write, in hope of meeting someone else?s acceptance and approval. Talk about messing with your self-esteem, that will do it. You may have to spend money for them to even look at your writing. But when you do, you are almost assured they will tell you what you had hoped to hear ~ that your writing is absolutely wonderful!

You can pretty much guarantee that those who offer self-publishing will really love your writing, too. However, the price for encouragement, on that level, is considerably higher.

Then, there are contests wherein expense is required, either to enter or to claim your prize. In other circles, we call it gambling.

Though, if you are otherwise accepted, you may be required to pay for the honor of having your writing listed among them. However, unless you tell all your friends, no one that knows you will ever see it. And, all the rest won?t even remember your name.

Such as these take unfair advantage; manipulating the heart strings of those whose dream in life is to, one day, be a writer. In fact, most such cons stay within legalized limits; but steal from your wallet, none-the-less.

I am not a writer wanna be. In fact, I?m not even a writer. I do not seek to become a writer. But, I could keep going with this skeptism as, when I do write it is with motivation and purpose. Maybe I just have a lot of issues. :)

What got me going, this time, was a shared link to a web site implying they were interested in original Christian writing submissions. However, in addition to all else, they suggested that if you wait for the Spirit?s moving, you may never write. So, at that point, I was no longer annoyed but a bit ticked. If the Spirit isn?t in it, it shouldn?t be written. Shame on them!

When God inspires one to write, it does not need criticized. There are times when a different arrangement of words would read more smoothly. And, definitely, proofing helps the reader to be able to better absorb content. However, the intent in which God gave it should never be changed. God doesn?t do anything inferior. Only, some take it upon themselves to think they know more than God.

But, also, as is really obvious when the only accepted poetry submission is ?non-rhyming poetry?, regardless of content, those have pre-determined what is good poetry while they look down upon the rest. That might be a good deal, to at least know what is expected. Only, no two critics agree on what good poetry is.

So, there are no guidelines that the ?would be hopeful? can obtain ~ unless the writer throws out their own style, to match someone else?s, in hopes of being accepted into that group. And, that could even be a good thing, if only that group were a ?for real? publisher. But, what really happens is authors sell their soul to be accepted by a group of writer wanna be?s.

As it is with many, one?s dream of writing is not all that different from the self-defeating teen-age dream of, one day, winning the Miss America pageant; only with more substance. If you are fixed on becoming famous by the world?s methods, go right ahead and let the world keep kicking you in pants. As Christians, when we follow the majority, we lose sight of why we are writing and end up inviting our own defeat.

However, if you are inspired by Holy unction, you will write whether you ever become famous or not. And, when God inspires you to write, there are souls waiting for that message. If you ever get a glimpse into the importance, significance, and magnitude of that, you will share your writings whether you ever get paid or not ? and you will stop welcoming criticism. Our accuser?s name is Satan.

Also, when God inspires a writing, it doesn?t really belong to you. So, when ?represented to be? Christian (Christ like) people holler about copyrights, I start to lose respect for them. It is one thing for another to claim and or make a profit off your works. It is another to threaten and sue when someone has paid such a compliment as to share your writing with others it might, also, minister to. The same goes for all forms of Christian ministry. For however many ways God opens doors, the seed He gives can and should be multiplied again, and again.

It is God?s job to determine how many times one?s seed gets multiplied. Our part is to be available, faithful, and obedient to share that which He blesses us with. And, the more you share, the more God gives you to share. Also, the better you will get at it! Then, as it works in with God?s timing and you are spiritually prepared for what comes next, God will open more doors ~ then more.

If your calling leads in the direction of publishing, publishers will find you. For others, writing may have helped develop confidence in being a better speaker. Whatever your path in life is to be, He who calls you will also do it. His yoke is easy and that takes the pressure off us.

Let us forget the wanna be?s and put our focus on being a servant. God makes all things beautiful, when it is time.

2004 by Joyce C. Lock
http://our.homewithgod.com/heavenlyinspirations/

But this I say, He which soweth sparingly shall reap also sparingly;
and he which soweth bountifully shall reap also bountifully.

Every man according as he purposeth in his heart, so let him give;
not grudgingly, or of necessity: for God loveth a cheerful giver.

And God is able to make all grace abound toward you;
that ye, always having all sufficiency in all things,
may abound to every good work.

2 Co. 9:6-8

This writing, as well as all of Joyce C. Lock?s
writings, may be individually used, in their entirety,
with credits in tact; for non-profit ministering purposes

Joyce C. Lock is a published author, poet, and columnist. In addition, she founded and maintains the e-mail ministries ?Heavenly Inspirations?
http://our.homewithgod.com/heavenlyinspirations/ and ?Share a Smile? http://groups.yahoo.com/group/smilesharing/ . Joyce?s writings encourage us in our relationship with God and each other.

Written on October 14th, 2012
Read more articles on Become a writer.

Source: http://www.copywritinghelp.net/become-a-writer/writer-wanna-bes-5/

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Readers' Pets | Janet Evanovich

New readers? pets are posted every Monday.? Send your pet?s picture (jpg or gif) along with your pet?s name to webmaster@evanovich.com.? (Please don?t use photo sharing websites as most galleries expire before we can get to your picture.)

Click on a picture to enlarge it, and read the caption.

Source: http://www.evanovich.com/2012/10/readers-pets-49/

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Monday, October 8, 2012

Friends baffled by killing of Ala. college student

(AP) ? Classmates and friends are questioning why a police officer fatally shot a University of South Alabama freshman who was naked and had been banging on a window at police headquarters.

Campus officials didn't give any indication that Gil Collar, 18, of Wetumpka had a weapon when he was shot. A university spokesman said he was fatally wounded about 1:30 a.m. Saturday after an officer heard a bang on a window and went outside to investigate.

A statement issued by university spokesman Keith Ayers said Collar, who wrestled at Wetumpka High School before enrolling at South Alabama, assumed a "fighting stance" and chased an officer before being shot. The officer tried to retreat numerous times to defuse the situation before opening fire, the school said.

But sophomore Tyler Kendrick said campus authorities haven't provided any satisfying answers about why Collar was killed.

"Really, it just upsets me that there's no other way to apprehend an unarmed student rather than shooting him. I don't understand that," Kendrick said.

Joshua Frye said it seemed the officer could have used something other than a firearm to stop Collar.

"What I feel is that a cop has more than a gun ...," he said.

The officer was placed is on paid leave, and an autopsy will determine if drugs or alcohol were involved.

Campus officials said the confrontation was recorded by security cameras. The video and other information has been turned over to the district attorney and the Mobile County Sheriff's Office, which will review the shooting.

Colgan Meanor went to high school with Collar and then enrolled at the same college.

"He was a great, loving guy who always made people smile," she said. "He's not the kind of guy that people knew him and said he would do something like this."

Collar was the second person killed on the South Alabama campus since last year.

A university freshman was charged with murder in the fatal stabbing of another teenager who was slain in an on-campus apartment in July 2011. The victim was a visitor to campus and was not enrolled, authorities said.

Ayers said South Alabama, located near downtown Mobile, was still "a very safe campus" despite Collar's death.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-10-07-Naked%20Student%20Shot/id-0622b7afadf44304a96e7857206db566

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Sunday, September 30, 2012

White shark diets vary with age and among individuals

ScienceDaily (Sep. 28, 2012) ? Many white sharks shift from fish to marine mammals as they mature, but individual sharks show surprising variability in dietary preferences.

White sharks, the largest predatory sharks in the ocean, are thought of as apex predators that feed primarily on seals and sea lions. But a new study by researchers at the University of California, Santa Cruz, shows surprising variability in the dietary preferences of individual sharks.

The researchers described their findings in a paper published online September 28 in PLoS ONE. They analyzed the composition of growth bands in shark vertebrae to trace variations in diet over a shark's lifetime. Stable isotopes of carbon and nitrogen incorporated into an animal's tissues serve as a natural tracer of dietary inputs.

"We did find that white shark diets changed with age, as expected, but we were surprised that the patterns and extent of change differed among individuals," said Sora Kim, who led the study as a UCSC graduate student and is now at the University of Wyoming.

The researchers analyzed vertebrae of 15 adult white sharks that had been caught along the west coast (14 off California and one off Baja California). Sharks in this population consume a wide range of prey, including seals, sea lions, dolphins, fish, and squid. But not every shark eats the same mix of prey, said coauthor Paul Koch, professor of Earth and planetary sciences at UCSC.

"We confirmed that the diets of many individuals observed at seal and sea lion rookeries shift from fish to marine mammals as the sharks mature," he said. "In addition, we discovered that different individual sharks may specialize on different types of prey. These two types of flexibility in feeding behavior are difficult to document using traditional methods, but may be very important for understanding how the population is supported by the eastern Pacific ecosystem and how it may respond to changes in that ecosystem."

The National Oceanic and Atmospheric Administration (NOAA) recently announced that it will consider whether to protect the west coast population of white sharks under the Endangered Species Act.

Tagging studies have shown that the white sharks found along the California coast have a regular migratory pattern, cruising coastal sites from late summer to early winter and moving to offshore areas during the rest of the year. While sharks within this population may have predictable movement patterns, the new study shows that there are important dietary and behavioral differences among individual sharks.

The study relied on vertebrae obtained from white shark specimens in various collections. The sharks had been caught at different times and places along the coast from 1957 to 2000. "Interestingly, we do see a small shift in diet as marine mammal populations increased after the passage of the Marine Mammal Protection Act in 1972," Kim said.

In addition to Kim and Koch, the coauthors of the paper include James Estes, professor of ecology and evolutionary biology at UCSC, and Tim Tinker, a biologist with the U.S. Geological Survey and adjunct professor of ecology and evolutionary biology at UCSC. This research was funded by the National Science Foundation.

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Story Source:

The above story is reprinted from materials provided by University of California - Santa Cruz. The original article was written by Tim Stephens.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Kim SL, Tinker MT, Estes JA, Koch PL. Ontogenetic and Among-Individual Variation in Foraging Strategies of Northeast Pacific White Sharks Based on Stable Isotope Analysis. PLoS ONE, 2012 DOI: 10.1371/journal.pone.0045068

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/strange_science/~3/jMjVYCiUi9g/120929140238.htm

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Monday, September 24, 2012

Researchers develop editing toolkit for customizing zebrafish genomes

ScienceDaily (Sep. 23, 2012) ? Mayo Clinic researchers and an international team of scientists have developed a highly-efficient means of editing zebrafish genomes for research purposes, eliminating a bottleneck that has stymied biomedical scientists from using the fish as a model for human disease.

The details appear online today in the journal Nature.

For many researchers, zebrafish are becoming the model of choice for genetic studies. However, the inability to efficiently target genetic modifications has delayed their use by some. The Mayo team used an improved variant of artificial transcription activator-like effector nucleases, or TALENs, to provide a new approach.

"By using genetic engineering tools called TALENs and synthetic DNA to make defined changes in the genomes of our fish, we are able to make small changes (just a few nucleotides) as well as add a specific sequence for biological gene switch applications," says Stephen Ekker, Ph.D., senior author and head of Mayo's zebrafish core facility. "This is the first time we've been able to make custom changes to the zebrafish genome."

Dr. Ekker says this toolkit opens the door to a range of new experiments in zebrafish, including modeling of human disease by introducing small point mutations, designing regulated gene alleles, and developing classical structure/function experiments using an animal model system.

This new approach has implications for other model systems, including mice, rats, flies and worms, and possible applications in stem cell research.

"To our knowledge, this TALEN toolkit also is the most active described to date," says Dr. Ekker. "This has important implications for the growing TALEN field, whether used in fish or any other cells. We used this higher activity for genome editing applications. We also used it to conduct a series of somatic gene function assessments, opening the door to an array of non-germline experiments in zebrafish."

Other authors include Victoria Bedell, Jarryd Campbell, Tanya Poshusta, Randall Krug, Sumedha Penheiter, Ph.D., Alvin Ma, Ph.D., and Karl Clark, Ph.D., all of Mayo Clinic; Ying Wang, Ph.D., and Jeffrey Essner, Ph.D., of Iowa State University; Colby Starker, Ph.D., Wenfang Tan, Ph.D., Scott Fahrenkrug, Ph.D., Daniel Carlson, Ph.D., and Daniel Voytas, Ph.D., all of the University of Minnesota; and Anskar Y. H. Leung, M.D., Ph.D., of Queen Mary Hospital, Hong Kong.

Support for the research came from the State of Minnesota, the National Institutes of Health, the National Science Foundation, the Research Grant Council of the University of Hong Kong and the Tang King Yin Research Fund.

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Story Source:

The above story is reprinted from materials provided by Mayo Clinic.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Victoria M. Bedell, Ying Wang, Jarryd M. Campbell, Tanya L. Poshusta, Colby G. Starker, Randall G. Krug II, Wenfang Tan, Sumedha G. Penheiter, Alvin C. Ma, Anskar Y. H. Leung, Scott C. Fahrenkrug, Daniel F. Carlson, Daniel F. Voytas, Karl J. Clark, Jeffrey J. Essner, Stephen C. Ekker. In vivo genome editing using a high-efficiency TALEN system. Nature, 2012; DOI: 10.1038/nature11537

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/NY5ZSCdufwk/120923141214.htm

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Monday, September 17, 2012

Vick rallies turnover-prone Eagles past Ravens

By ROB MAADDI

AP Pro Football Writer

Associated Press Sports

updated 7:52 p.m. ET Sept. 16, 2012

PHILADELPHIA (AP) - With the game on the line, Michael Vick made all the right decisions - again.

Vick scored on a 1-yard TD run with 1:55 left, helping the Philadelphia Eagles overcome a slew of turnovers to beat the Baltimore Ravens 24-23 on Sunday for their second straight comeback win.

The Eagles are 2-0 for the first time since Donovan McNabb and Terrell Owens led them to the Super Bowl in 2004.

"In the moment, you have to be at your best," Vick said. "It's got to be an any-means-necessary mentality."

Rookie kicker Justin Tucker made field goals of 56, 51 and 48 yards for the Ravens, but Joe Flacco couldn't get Baltimore (1-1) in his range in the final minute.

Flacco overthrew Ray Rice on fourth-and-1 from the Ravens 46, and the Eagles ran out the clock.

Vick threw four interceptions at Cleveland last week, but rallied the Eagles to a 17-16 win.

He did it again, though the replacement officials almost made a costly mistake.

Down 23-17, the Eagles started at their 20 with 4:43 left. Vick threw passes of 24 and 13 yards to Brent Celek. A 19-yard pass to Clay Harbor coupled with a roughing-the-passer penalty put the ball at the 3.

Vick then threw incomplete as he was being hit by Haloti Ngata, but the play was ruled a fumble and it was recovered by the Ravens. A replay overturned the call and Vick scored on the next play.

"There's some serious calls the refs missed," Baltimore's Ray Lewis said. "It's just the way it is, man, all around the league. We have to correct that. These games are critical. Guys are giving everything they've got all across the league. But these are calls, with the regular refs, if they were here, we know the way the calls would be made."

The Eagles committed three turnovers in the red zone in the first half and lost two starting offensive linemen in the second. They have nine turnovers in two games, a major reason why they only have 41 points despite totaling 942 yards of offense.

"We have to get better at it," coach Andy Reid said. "You have to take care of the football. You have to throw the football to the right person. This isn't something we planned on having."

Vick finished 23 of 32 for 371 yards with one touchdown and two interceptions. Celek had eight catches for 157 yards and DeSean Jackson had seven receptions for 114 yards.

This was a homecoming of sorts for Flacco and Ravens coach John Harbaugh. Flacco grew up in nearby Haddon Township, N.J. Harbaugh spent 10 seasons as an assistant under Reid before going to Baltimore in 2008.

Tucker almost made them winners.

An undrafted rookie out of Texas, Tucker beat out veteran kicker Billy Cundiff in the preseason and has made all six of his field goals in the first two games.

Tucker's 56-yarder at the end of the first half sent the Ravens into the locker room up 17-7. His 51-yarder early in the fourth made it 20-17.

Cundiff was 1-for-6 from beyond 50 yards last year, and missed a potential game-tying, 32-yarder against New England in the waning seconds of the AFC championship game.

"I think we'll be just fine coming out of this going forward," Harbaugh said.

Two plays after center Jason Kelce sprained his right knee and was carted back to the locker room, the Eagles got within 17-14 on Vick's 23-yard TD pass to Jeremy Maclin. Vick scrambled to his left and threw on the run to Maclin, who slipped behind coverage and went to his knees to make a nifty catch.

Philadelphia lost two more starters on its next drive. First, King Dunlap left with a hamstring injury. Maclin was then carted off with a hip pointer after making a block on Celek's 24-yard catch. Celek hurdled Ed Reed to gain a few extra yards on the play. Still, the Eagles reached the 5 before settling for Alex Henery's tying 23-yard field goal.

The starting quarterbacks were coming off opposite performances in Week 1. While Vick struggled against the Browns, Flacco was near-flawless in a dominant 44-13 win against Cincinnati last Monday night.

Flacco was 22 of 42 for 232 yards, one TD and one interception against Philadelphia.

Despite the makeshift line blocking for him, Vick didn't take as many hard hits and was sacked only twice. He scrambled eight times for 36 yards before kneeling twice at the end.

Using the no-huddle from the start, the Eagles moved the ball effectively to the Ravens 12. But Vick made another errant throw and was intercepted in the end zone by Bernard Pollard. Vick scrambled out of the pocket and had space, but he fired opposite his momentum.

"You can't always hit a home run," Vick said. "Sometimes you have to settle for singles and doubles. That's what I have to learn. I can't force the ball."

Trent Cole stripped Flacco on Baltimore's second play and Cullen Jenkins recovered at the Ravens 15.

McCoy ran in from the 1 for a 7-0 lead.

Vonta Leach scored on a 5-yard TD run to tie it at 7.

After the Ravens failed to convert on a fake punt - Sean Considine ran 3 yards on fourth-and-4 - the Eagles took over at Baltimore's 45. The drive ended in another turnover. Rookie Bryce Brown fumbled a handoff on third-and-1 at the 20, and Albert McClellan recovered at the 30.

Flacco connected with Jacoby Jones on a 21-yard TD pass to give the Ravens a 14-7 lead.

The Eagles drove to the Ravens 9 before Lardarius Webb caused McCoy to fumble. Lewis recovered and was slammed down to the ground by Vick. McCoy had one fumble last year when he was an All-Pro. He already has lost two in two games.

Notes: Rice ran for 99 yards and caught six passes for 53 more. ... Eagles improved to 5-9 in home openers under Reid and won one for first time since 2008. ... Tucker's 56-yard FG tied Wade Richey for longest in Ravens history. ... Entering the season, McCoy had lost one fumble in the previous 28 games, spanning 565 touches. He lost his second on his 36th touch. ... Dallas Reynolds replaced Kelce at center and took his first snap in the NFL.

---

Follow Rob Maaddi on Twitter: https://twitter.com/RobMaaddi

---

Online: http://pro32.ap.org/poll and http://twitter.com/AP-NFL

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Sunday, September 9, 2012

Eastwood talks about convention chat with chair

Actor Clint Eastwood addresses the Republican National Convention in Tampa, Fla., on Thursday, Aug. 30, 2012. (AP Photo/Charles Dharapak)

Actor Clint Eastwood addresses the Republican National Convention in Tampa, Fla., on Thursday, Aug. 30, 2012. (AP Photo/Charles Dharapak)

(AP) ? Clint Eastwood said the idea to use an empty seat as a prop at the Republican National Convention was a spur-of-the-moment decision when someone backstage asked if he wanted to sit down.

In his first interview since his Aug. 30 appearance at the convention to pledge support for GOP presidential candidate Mitt Romney, Eastwood told the Carmel Pine Cone that his speech was not only unscripted, it was pretty much spontaneous.

"There was a stool there, and some fella kept asking me if I wanted to sit down," Eastwood told the weekly newspaper in the small California city where he once was mayor. "When I saw the stool sitting there, it gave me the idea. I'll just put the stool out there and I'll talk to Mr. Obama and ask him why he didn't keep all of the promises he made to everybody."

Eastwood's peculiar, sometimes rambling conversation with an imaginary President Barack Obama in an empty chair set the blogosphere and social media ablaze. Reaction to his appearance generally has split along party lines, with Republicans raving about his stinging rebuke of Obama and Democrats ridiculing him as old, angry and out of touch.

The 82-year-old Eastwood said he set out to make three points and he achieved his goal.

"That not everybody in Hollywood is on the left, that Obama has broken a lot of the promises he made when he took office, and that the people should feel free to get rid of any politician who's not doing a good job," Eastwood said in the interview, which was conducted Tuesday but not published until Friday. "But I didn't make up my mind exactly what I was going to say until I said it."

Political conventions normally are tightly scripted and Romney's campaign aides had wanted details about what Eastwood planned to say.

"They vet most of the people, but I told them, 'You can't do that with me, because I don't know what I'm going to say,'" Eastwood said.

Eastwood acknowledged his presentation was "very unorthodox" but said he knew that would be the case.

"They've got this crazy actor who's 82 years old up there in a suit," he said. "I was a mayor, and they're probably thinking I know how to give a speech, but even when I was mayor I never gave speeches. I gave talks."

Eastwood said he was told to speak for five minutes but he said it was difficult to gauge time and there weren't any signals or cues telling him to wrap up. He ended up speaking for about 12 minutes.

Romney and his running mate, Paul Ryan, later came backstage to thank him.

"They were very enthusiastic, and we were all laughing," Eastwood said.

Eastwood, who stars in the upcoming movie "Trouble with the Curve," maintains Obama doesn't deserve a second term as president.

"President Obama is the greatest hoax ever perpetrated on the American people," Eastwood said. "Romney and Ryan would do a much better job running the country, and that's what everybody needs to know. I may have irritated a lot of the lefties, but I was aiming for people in the middle."

Despite all the attention he received, Eastwood hadn't granted any interviews since his speech. Even his longtime manager, Leonard Hirshan, told The Associated Press he was unaware Eastwood had spoken to the newspaper.

"You're telling me something for the first time," Hirshan said.

Hirshan stressed that as a manager, he wouldn't necessarily know about Eastwood's dealings with the media. The actor has no publicist.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2012-09-07-Convention-Clint%20Eastwood/id-d75418f52afa418ca1f2b6dbd723d1de

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Sunday, September 2, 2012

A Girl and Her Pig with Jen Louis of Lincoln Restaurant -

September 1, 2012 By Food Dude 3 Comments Lincoln Bacon Apple Pie

Lincoln Bacon Apple Pie

Author April Bloomfield of A Girl and Her Pig book tour, joined up with chef Jenn Louis of Lincoln Restaurant for a Portland tour. It?s a nice look at Sauvie Island Organics, Breakside Brewery, Olympic Provisions, and of course, Lincoln.

"I have a wide-range of food experience - working in the restaurant industry on both sides of the house, later in the wine industry, and finally traveling/tasting my way around the world. Whether you agree or disagree, you can always count on my unbiased opinion. I don't take free meals, and the restaurants don't know when, or if, I am coming."

Source: http://www.portlandfoodanddrink.com/a-girl-and-her-pig-with-jen-louis-of-lincoln-restaurant-2/

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Tuesday, August 21, 2012

BondAdpp?tit: Milk Tea Mondays: Tea Lane

Tucked away in the corner of a Hong Kong supermarket plaza lies a fairly new tea shop called Tea Lane. Established this year, Tea Lane is a quaint, homey tea shop with a touch of sophistication. ?Their barista area looks so classy that it would make other coffee shops jealous.

It's a small, inviting shop that boasts a reasonably priced food and drinks. Their food is Taiwanese and they have a special combo menu that is only $6 per combo. ?This deal is only from 11:30am-9:30pm, so plenty of time to order it! From this combo menu, I ordered their cold noodles. ?It came with a warm salad and my choice of two skewers.


The bowl of noodles looked small but it was very filling. ?It came with minced beef and topped with bean sprouts. ?It was flavorful and had enough seasoning to it. ?The warm salad that came with it was a bit bland and I didn't really eat that much of it.

I ordered the lamb and chicken gizzard skewers. ?You tell your waiter how much spice you want on it. ?I asked for medium but that still was not spicy enough for me. ?The skewers had Indian flavors to it and the smell of the spices were strong. ?I liked both and I'm glad the chicken gizzard was not over-chewy.?

Our waiter recommended the Hokkaido milk tea. ?At first, I could not put my finger on the taste of it. ?My friend said that it had a hint of barley tea flavor. ?It was very smooth, creamy, and milky. ?It did not have a hint of powder in it. ?I came here a second time and finally ordered an almond milk tea.?

I was a bit disappointed in their almond milk tea. ?Like the Hokkaido milk tea, it was smooth and milky; however, it was completely lacking the almond flavor. ?It was not too sweet but I felt that I was drinking just flavored water. ?I like this place so I'll overlook the almond milk tea and try other things on their menu.

Service:?Impeccable. ?The waiters are friendly, polite, and would come by and ask you how everything is going. In addition, if you are?unsatisfied?with your drink, they will take it back and make it less strong, add more sugar, or whatever your request is.

Price: ?Reasonable. ?Drinks range from $3-$4 but they serve it in a huge mug. ?The $6 combo is also a great deal. My waiter said it was the smaller meal but it satiated my appetite. ?There is another special combo for about $11 that I may look into next time.

Food and drink: ?Despite my disappointment in their almond milk tea, I liked the Hokkaido milk tea. ?I also sampled a few sips from my friends' drinks and I liked their orders too. Their skewers are tasty but not a fan of their salad. ?I'm interested in tasting the rest of their menu.

Tea Lane is not as crowded as other places, which I like. ?I will definitely be coming back since I have a stamp card to fill. ?They accept card but it is a minimum of $10, so better bring cash. Tea Lane also offers free Wi-Fi! Since it's located in the Hong Kong supermarket plaza, parking is readily available. Check it out!

Tea Lane
18414 E. Colima Rd.
Unit R
Rowland Heights, CA 91748
626-575-9998

Business Hours: Mon-Tues, Sun: 11:30am-11:30pm. Fri-Sat: 11:30am-12am.

Thank you for reading!

Source: http://bondadppetit.blogspot.com/2012/08/milk-tea-mondays-tea-lane.html

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Tuesday, July 31, 2012

Cosmetic Surgery And its particular Effects! ? Guru Article Directory

Many men fall for ladies who possibly possess stunning eyes, long and also glistening hair, or perhaps a body toned. All these capabilities not just attract the opposite gender, although likewise make a lady sense self-assured of your ex visual appeal. Conditions, like childbirth, fat loss, ageing, as well as health issues, detrimentally affect some sort of women?s body and skin area. Scars, unfastened epidermis, and darkish sectors mar their own entire looks. Girls do every thing to remove these kinds of problems. They would hide stretch marks along with clothing, conceal their particular black communities at the rear of eyes cosmetics, and utilize the most popular epidermis tightening lotion regarding free epidermis. Despite all these efforts, they still turn out splurging several hours plastic surgical procedures.

Cosmetic surgical treatments can damage your skin
Cosmetic surgery is a sort of plastic cosmetic surgery that is executed to take care of facial lines, pads, stretch-marks, unfastened skin area, and a lot of these kinds of epidermis associated problems. In this particular process, a little br?che is created nearby the tresses collection for you to lift up skin and also take away unnecessary tissues. These kinds of surgeries are pretty costly, and they are conducted by specialized doctors. Additionally , these people demand rigorous post-operative proper care, as assembl?e as well as blood clots inside the run spot go on a fine timeframe to be able to cure. Additional, aesthetic surgical treatments have got a variety of unwanted side effects, for instance swelling, physical modifications, and pores and skin allergic reactions.

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In spite of it is a number of effects, surgery treatment is still throughout large demand for the fast outcomes.

Because going through any plastic surgery usually takes merely a day or two, folks are ready to shell out a premium price for it. Still nothing at all can make on with the problems it can towards your skin area and also human body, and for the long injure therapeutic time period.

Additionally, the spot handled through surgery treatment loses the organic factor, and appears manufactured as well as strange occasionally. These types of surgeries also neglect to get the wanted looks, as well as instead make the controlled aspect appearance unsightly. Aesthetic treatments may also generate some other health hazards. In such scenarios, people are not able to do anything much more expressing feel dissapointed about. Absolutely nothing brings backside their particular all-natural look. You should utilize an ointment, or possibly a lotion that would offer you the natural way more youthful appear, regardless of slow its.

Many people may right now believe that the skin tightening up lotion is actually a better option entirely. Which is correct! An epidermis tightening up product is exceedingly economical, as compared to aesthetic surgical procedures. In addition, these lotions will get the position kept away from virtually any negative effects.

Utilizing a medically proven system is a much healthier and faster way of eliminating free facial skin, and also heavy facial lines.

The most effective age reversing ointment, or skin tightening up ointment will make your skin appearance more youthful although dealing with all of the mentioned skin area difficulties. Select products which are kind for your skin, and still have no unwanted effects. Do not often go for creams along with faster final results, though prefer those along with better results. There are several items available on the market which could retain in which all-natural facet of the skin.

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Source: http://guru3x.com/cosmetic-surgery-and-its-particular-effects/

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Sunday, July 22, 2012

Honestly, I? :: Living the Dream Coaches

Written by: Joe Battaglia on July 21, 2012.

?

What would happen to your various relationships (your spouse or significant other, your parents, your children, your friends? you get the idea) if you decided to be honest about everything? No fair lying, just the straight truth. Strangers don?t count because they have no expectation of your behavior.

Some would, no doubt, think you had lost it. In the short run, it might get you in a world of trouble. But in the long run, wouldn?t life be a lot simpler? If people knew that they could count on you to give them an honest answer if they asked for it, do you think you might get a lot more questions? It worked for George Washington (the cherry tree) and good old ?Honest Abe.?

OK, let?s get serious now. We all know what happens to people who tell the truth all the time; just watch the movie ?Liar, Liar.? People just aren?t ready for that kind of raw reality. People need that artificial shading, that ?La vie en Rose? to their lives.

So I just want to zero in on one relationship in particular. That one relationship where, ideally, you can say anything and it will only make the relationship stronger; the one place where this sort of honesty can be the bedrock for the kind relationship that can last a lifetime.

Can you imagine a marriage (or committed) relationship where there are no mind games, no ?I wonder what she meant when she said?? no ?He?ll get the message when I??? Just straight talk where you know what you say won?t be taken the wrong way because everything that is said and done comes with the guarantee of love and commitment.

Is it hard to pull off? Yes it is. Is it impossible? No it?s not. It takes work. It takes commitment. It takes trust in the knowledge that that other person will always be at your side no matter what. It?s called unconditional love.

Do people change? Yes, and if you respect each other, you will grow together in ways that will allow you to complement each other and make you stronger together than you are apart.

Look, I know this is hard, but the reward for this honesty and commitment is a lifetime relationship with someone who really cares.? Isn?t that worth the effort? Isn?t that what life is really all about?

I know it is because I?ve found it.

Source: http://livingthedreamcoaches.org/honestly-i/

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Friday, July 20, 2012

On Deck, a sports calendar for July 19 - Bangor Daily News

BASEBALL

Sunday Recreational Baseball

At Newton, Mass., Henry Baseball is looking for new players ages 16 to 45 to play Sundays at 11 a.m., games are finished by 2 p.m.; league also needs coaches and volunteers; contact Henry at 781-891-0621

CANOE RACING

Saturday, July 21

At Fort Fairfield, Forbes Landing on Aroostook River, Regatta on the Aroostook, canoe and kayak race, registration 3-4:30 p.m. 6.5 miles of flat water, $10 per person, for info contact 472-3882 or 227-6306

CYCLING

Sunday, July 22

At Fort Fairfield, Fort Fairfield Community Center, Spud Cycle Classic Bicycle Race, registration 8 a.m., 25- and 12-mile races start at the Blockhouse on Main Street, $15 per rider, for info contact 472-3882 or 227-6306

CHEERLEADING

Spirit Camp

At Orono, University of Maine Student Recreation Center, July 25-27, 9 a.m. to 3 p.m., grades 1-6, instruction will be provided by the University of Maine Cheerleaders; for more info, email Spiritcheercamp@aol.com, or call Tami Campbell at 862-3355.

FOOTBALL

UMaine High School Day Camp

At Saco, Thornton Academy, University of Maine football team high school day camp, July 26, 4:30 p.m. to 8 p.m., $25 per person; Black Bear coaches will conduct drills and competitions, only equipment needed is cleats; to register or for more information, contact coach Shawn Demaray at shawn.demaray@umit.maine.edu; deadline is July 23; players must fill out medical and risk forms, available at GoBlackBears.com, and take them to the camp.

7-on-7 Camp

At Orono, University of Maine, Alfond Stadium, UMaine football team?s 7-on-7 High School Tournament, July 28, ?two-hand touch? event includes morning round-robin play and single-elimination playoffs in the afternoon, UMaine coaches will officiate; $150 per team, athletes should bring a lunch, snacks, footballs, a jersey, sneakers and cleats; no pads needed; cost includes UMaine T-shirt; to register or for information, contact coach Shawn Demaray at shawn.demaray@umit.maine.edu by July 20; players must fill out medical and risk forms and take them to the camp.

GOLF

Saturday, July 21

At Fort Fairfield, Aroostook Valley CC, Potato Blossom Festival Golf Scramble, three-person scramble, minimum team handicap of 30, for info contact AVCC 800-980-8747 or 207-476-8083.

Friday, Aug. 3

At Rocky Knoll CC, Orrington, Brewer High School?s Class of 1967 Golf Scramble, 1-4 p.m., $25, prizes, tourney benefits BHS Scholarship Fund, alumni and friends welcome, sign up at Rocky Knoll or contact Lynn Hunt at 989-5876 or on the BHSClassof67 website

Saturday, Aug. 4

At Pine Hill GC, Brewer, first Brooksy Birdies, Bogeys & Beer Golf Tournament, four-person scramble, 8 a.m., $40 a person, for info or to enter contact Jason Brooks 356-7960, Katie LaChance 735-6775, or Jay Collier at Pine Hill 989-3824, rain date Aug. 5.

Saturday, Aug. 18

At Rocky Knoll CC, 7th annual John Bapst Hockey Boosters Golf Tournament, noon registration, 1 p.m. shotgun start, prizes, team entry of $300 includes carts, meals, mulligans, for more information, visit www.johnbapst.org or contact Melissa Harvey at 207-949-7535 or email mharvey1324@gmail.com.

ROAD RACING

Saturday, July 21

At Fort Fairfield, Main Street, across from Hillside IGA, Potato Blossom 5-Mile Road race, preregistration 7:30 a.m., walkers start 8:30 a.m., runners at 9 a.m.; $15 per person, contact Paul Lamoreau 764-6517

Saturday, Aug. 4

At Carmel, Carmel Days 5K, registration 7:30 a.m. at Carmel rec. field, race starts 8:45 a.m., entry fee $20 on race day or $15 preregister at www.camrelrec.com

At Fort Kent, UMaine-Fort Kent athletic department?s 5K summer fun run, 8 a.m. race-day registration at UMFK Sports Center, race begins at 9 a.m., $20 entry fee, benefits Dylan R. Levesque Memorial Scholarship, rain date Aug. 5, for info contact Eric Werntgen 834-7828 or or register online at: at: http://athletics.umfk.maine.edu/funrun/

At Dover-Foxcroft, 16th Annual Pony Pride Alumni 5K, 7 a.m. registration at YMCA on Park Street, 8 a.m. start, $15 race-day fee or $12 preregistration, held in conjunction with Foxcroft Academy?s Alumni Weekend, parade follows race

Saturday, Aug. 11

At Calais, 33rd Annual Johnson?s 5-Mile International Road Race, 9 a.m., contact the Calais Rec Department 454-2761 or calaisrec@calaismaine.org

SOCCER

Saturday, July 21

At Caribou, ski building, Caribou High School athletic complex, Northern Maine Board of Approved Soccer Officials clinic for prospective soccer officials, 9 a.m. to 4 p.m., clinician is Bob Stedt, NMBASO Rules Interpreter; anyone age 18 or older who is interested in officiating soccer this fall on the middle school and junior varsity levels in Aroostook County is urged to attend, $35, preregistration is recommended; contact Bob Stedt at 896-5501, 896-5514 or 540-2550, or by email at rstedt@maine.rr.com.

TRIATHLON

July 21-22

At Fort Fairfield, Maine Potato Blossom Festival Triathlon, combines participants? times from Potato Blossom canoe race, road race and cycling race.

Source: http://bangordailynews.com/?p=1195424

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